Isolation and Evaluation of Tamarind Seed Polysaccharide being used as a Polymer in Pharmaceutical Dosage Forms
نویسندگان
چکیده
Tamarind seed polysaccharide (TSP) obtained from the seed kernel of Tamarindus indica, possesses properties like high viscosity mucilage, broad pH tolerance, no carcinogenicity, mucoadhesive nature, and biocompatibility. It is used as stabilizer, thickener, gelling agent, and binder in food and pharmaceutical industries. The objective of present investigation was to search for a cheap and effective natural excipient that can be used as an effective alternative for the formulation of pharmaceutical formulations. Thus this mucilage will be a non-toxic, bio-degradable, cheap, economic and easily available option as a natural polymer.
منابع مشابه
Extraction and Characterization of Tamarind Seed Polysaccharide as a Pharmaceutical Excipient
Objective: the objective of the present work was extraction of polysaccharide from tamarind seed and further characterization as pharmaceutical excipient. study includes phytochemical screening, micromeritic properties. Work also emphasize to study gelling properties of extracted polysaccharide. Methods: Water based extraction procedure was used to extract polysaccharide from tamarind seed. Pha...
متن کاملTamarind Seed Polysaccharide and its Modifications- Versatile Pharmaceutical Excipients – A Review
In recent years there has been an important development in different dosage forms for existing and newly designed drugs and natural products, semisynthetic as well as synthetic excipients often need to be used for a variety of purposes. Gums and mucilages are widely used natural materials for conventional and novel dosage forms. With the increasing interest in polymers of natural origin, the ph...
متن کاملSynthesis, characterization and evaluation of thiolated tamarind seed polysaccharide as a mucoadhesive polymer.
In the present study, thiol-functionalization of tamarind seed polysaccharide was carried out by esterification with thioglycolic acid. Thiol-functionalization was confirmed by SH stretch in Fourier-transformed infra-red spectra at 2586 cm(-1). It was found to possess 104.5 mM of thiol groups per gram. The results of differential scanning calorimetry and X-ray diffraction study indicate increas...
متن کاملExtraction and Characterization of Tamarind (Tamarind indica L.) Seed Polysaccharides (TSP) from Three Difference Sources.
Tamarind seed polysaccharide (TSP), a natural polysaccharide extracted from tamarind seeds is used in the pharmaceutical, textile and food industries as a mucoadhesive polymer. This work aimed to extract TSP from tamarind seeds from three sources with two methods and characterized its physical and chemical properties. Kernel powder of tamarind seeds was slurried into a clear solution, set aside...
متن کاملGelation and gel properties of polysaccharides gellan gum and tamarind xyloglucan
Polysaccharide is used widely in food, cosmetic and pharmaceutical industries. The main use is to give appropriate texture to the products. Thus the polysaccharides used in such way are called texture modifier. Here two important texture modifiers, gellan and tamarind xyloglucan are introduced. The former one is a microbial polysaccharide with gelling ability. Gelling ability makes gellan valua...
متن کامل